Question 2
This study included both sporadic cases of ALS and Familial. The researchers state some studies found that familial ALS has higher mREE than sporadic ALS patients. This study did not look into the differences between the two. Do you think this could affect the results of the study? If so how would you have set up the study to account for the differences in energy needs?
posted by Jordan @ 11:55 AM
10 comments
10 Comments:
The study stated that these difference were likely due to genetics determinants. The influence of genetics factors in ALS patients on metabolic rates would be an entirely different research project (and a big one I would imagine). I do not think that this would affect the results of this study to any large degree. For the purpose of this study and the ultimate question that they wanted to answer (which equation is the best) it seems acceptable that they did not look further into this result.
I don’t think that this factor would have affected the study so much that the results would have been thrown off. They calculated energy needs of each individual participant and found a trend in the results. I think that this study was set up well according to the purpose and goals of the researchers.
Agreeing with Stephanie, the methods were set up accurately for the purposes of the study and did not need to include the varying groups of ALS patients.
This study could serve as foundation for another study comparing the mREE rates of the different ALS patients. They could even throw out using the I.J. equations based on the results of this study.
I don't think this would affect the study results that much. I agree with what everyone else has said that this could be an entirely different research project. This study provides sufficient information for the objective of the study.
Yes this definitely could have affected the results of this study. If the researchers were aware of this difference and acknowledged it, I am surprised that the two cases were not discussed separately. I think that two conclusions should have been made, discussing each case and the result from those patients
I honestly do not know if this would affect the results of their study, so I think it would be beneficial to conduct a study to determine if it does.
Kevin-
I agree with you. If the researchers noted this difference, then why wouldn't they look at the two cases? Maybe they figured this was a good starting point for a study and hope to expand on it later. I'm interested to see where this research goes in the future.
Kevin-
I agree with you. If the researchers noted this difference, then why wouldn't they look at the two cases? Maybe they figured this was a good starting point for a study and hope to expand on it later. I'm interested to see where this research goes in the future.
I think that there could be some variation in the study since there is a noted variation in mREE. I would find it interesting to do a study to look at this, which could then either validate or disprove the results of this study.
I agree with Kevin. Considering they openly acknowledged there was a difference in the two groups, I am curious as to why they would still perform the test as it was done.
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